Bioinformatics

Bioinformatics

The Bioinformatics division at "UNIPRO" was launched in 2003 when our first specialized IT tool for biologists was developed and released. It allowed for pairwise comparison of complete genetic sequences of different species. Today, we are developing and supporting both our own bioinformatics products and custom projects.

UGENE

In 2008, the company's new flagship product in bioinformatics, UGENE, was introduced, and the company continues to actively develop it today. UGENE is free software for molecular biologists, available on Windows, macOS, and Linux. UGENE is very easy to install and use, integrating various tools and methods for comprehensive analysis of molecular sequences within a single multifunctional graphical interface.

The project supports flexible integration of third-party programs. For example, within the framework of grants funded by the European Union, the United States, and Russia, as well as through orders from commercial companies, tools for high-throughput sequencing data analysis, variant calling, transcriptomics, metagenomics, and much more have been added to the open version of UGENE.

In addition to the basic open version of UGENE, the company offers services for developing custom bioinformatics applications, accessible only to the client.

Today, development is focused on several areas: new algorithms for sequencing data processing, optimization of existing algorithms, improving the graphical interface, creating automated computational pipelines, integrating various new analysis methods, enabling biologists to work with databases, and implementing online services.

  1. Okonechnikov K, Golosova O, Fursov M, the UGENE team. Unipro UGENE: a unified bioinformatics toolkit. Bioinformatics 2012 28: 1166-1167. doi:10.1093/bioinformatics/bts091
  2. Golosova O, Henderson R, Vaskin Y, Gabrielian A, Grekhov G, Nagarajan V, Oler AJ, Quiñones M, Hurt D, Fursov M, Huyen Y. Unipro UGENE NGS pipelines and components for variant calling, RNA-seq and ChIP-seq data analyses. PeerJ 2014 2:e644. doi:10.7717/peerj.644

GeneCut

The GeneCut program is designed for conducting in silico experiments on gene assembly and molecular cloning. It is implemented as a web service. The program allows splitting nucleotide sequences into short and long blocks using proven scientific algorithms and then assembling new genetic constructs from the resulting fragments. Additionally, various auxiliary manipulations with amino acid and nucleotide sequences can be performed.

The results obtained in the program serve as a basis for subsequent laboratory experiments. Detailed reports generated by the program are stored in a cloud database. To start using the web service, all you need to do is create an account.